TFD™ Technology and Bio-Exosomal Hair Care by Simone Trichology

The TFD™ (Targeted Follicular Delivery) platform concentrates encapsulated actives exactly where we want them: the follicular niche, around the follicle opening and its micro-environment (peri-follicular area, sebaceous gland, adjacent matrix).

Thanks to this technology:

  • Actives are protected inside a lipid membrane from pH shifts, oxidation and incompatibilities within the formula.
  • It supports localised, non-invasive penetration, navigating the upper scalp layers without aggressive methods.
  • Each exosome carries a high load of active ingredients, with controlled, time-modulated release for sustained exposure.
  • The biomimetic membrane composition enhances cell affinity and biocompatibility, favouring local bioavailability and coherent signalling.

This is a non-medical cosmetic technology, created to raise the performance of hair formulations whilst maintaining excellent skin tolerance.

Within Simone Trichology, this TFD™ targeted follicular delivery platform is the basis of our bio-exosomal hair care and exosome hair treatment protocols for the scalp and hair fibre.

The biomimetic exosomes we work with in our bio-exosomal hair care

In this first generation of products with TFD™ Technology we work with two main profiles of biomimetic exosomes, enriched with botanical fractions rich in polyphenols, flavonoids and phytosterols:

Bio-exosomal hair care with vegan biomimetic exosomes

 

1. Azelaic Acid + Encapsulated Herbal Complex

Designed for oily scalps, flaking and microbiome imbalance.

This profile acts on:

  • The appearance of excess sebum and root shine.
  • Surface renewal and skin texture, reducing the look of hyperkeratinisation and build-up.
  • Peri-follicular comfort on reactive scalps or those prone to itching sensations.

Key botanicals encapsulated within the exosomes:

  • Chamomile (Matricaria chamomilla): helps soothe and soften.
  • Nasturtium (Tropaeolum majus): supports signals of vitality and a sensation of a more “oxygenated” scalp.
  • Burdock (Arctium lappa): assists with the removal of surface impurities and follicular residues.
  • Sage (Salvia officinalis): offers purifying and sebum-balancing properties.

2. Red Clover + Acetyl Tetrapeptide-3 + Beta-sitosterol

A profile focused on hair with reduced density, thinning tendencies and scalps that need support for homeostasis and anchoring.

  • Acetyl Tetrapeptide-3: supports the collagen III/IV network and laminins associated with the follicular anchoring structure.
  • Red Clover (Trifolium pratense): rich in isoflavones (including biochanin A); provides antioxidant and comfort benefits, helping to maintain a favourable peri-follicular micro-environment.
  • Beta-sitosterol: a widely used phytosterol in scalp cosmetics; contributes to balance and comfort around the follicle.

In both cases, the TFD™ platform is responsible for guiding these actives to the follicular niche and releasing them gradually, for consistent cosmetic performance.

These vegan biomimetic exosomes are designed specifically for exosome hair care applications, helping cosmetic actives reach the follicular niche with precision.

Bio-Exosomal Trichology: from idea to real exosome hair care

For many years we have had a clear vision: to bring cellular biotechnology and advanced signalling into scalp and hair care, with a purely cosmetic approach that can be reproduced in-clinic and at home. The level of technology required to do this with our desired precision simply did not exist – until now.

The EXOSOME LINE – Cellular Hair Biotech was created from that vision: seamlessly combining biomimetic exosomes, TFD™ Technology and advanced botanical–biotechnological complexes to offer high-precision protocols designed for modern trichological practice.

For clinics and salons, this translates into a scalable exosome hair treatment platform that remains fully cosmetic while bringing advanced cellular science into daily trichology practice.

What scalp and hair concerns can this exosome hair treatment address?

A complete architecture for the main scalp needs

Using TFD™ Technology and our bioexosomes, we have developed specific shampoos and treatments that cover the key scalp concerns:

 

Each reference combines TFD™ bioexosomes with peptide complexes, vitamins, azeloglycine, neurocosmetic agents, marine ingredients and botanicals to deliver scalable protocols: in clinic / salon and at home, with reproducible cosmetic results.

Benefits of TFD™ targeted follicular delivery for professionals and end-users

For the trichological professional

  • A scientifically supported platform, with detailed technical documentation on actives and mechanisms.
  • Standardised protocols, easy to integrate into daily practice (diagnosis + in-cabin treatment + home maintenance).
  • A differentiated line built on TFD™ biomimetic exosomes, positioning the centre as a reference in advanced hair science.

TFD™ targeted follicular delivery for advanced exosome hair treatment

For the end-user

  • Hair that feels fuller and more vital from the roots.
  • A more balanced, comfortable scalp, with improved control of oiliness, dandruff or sensitivity according to the chosen protocol.
  • Hair that appears stronger, smoother and shinier, without compromising on lightness or cosmetic elegance.

Bring Bio-Exosomal Trichology and exosome hair care into your clinic or salon

If you are a distributor, clinic or specialised salon:

  • Request the complete EXOSOME LINE – Cellular Hair Biotech portfolio.

  • Access technical training, protocols and supporting materials for your team.

  • Integrate a line powered by TFD™ Technology and biomimetic bioexosomes, designed to work with precision in the follicular niche.

Simone Trichology – Bioexosomal Trichology: the future applied to today’s hair.

TFD bio-exosomal hair care technology by Simone Trichology