Key benefits
- Updated formula, now with marine glycogen, coffee fruit extract, zinc PCA, amino acids, soy protein, ginseng, onion and rosemary extracts and sunflower seed oil.
- Made for early, seasonal or reactive thinning.
- Helps improve the feel of anchorage at the root.
- Supports the look of density and vitality.
- Helps keep the scalp comfortable and balanced.
- TFD System: biomimetic follicular-release exosomes with red clover, acetyl tetrapeptide-3 and beta-sitosterol.
- Step 1 of the routine; pair with leave-in DNA Hairmax Pro Plus.
Key actives
- TFD System (biomimetic follicular-release exosomes) + Trifolium Pratense Extract, Acetyl Tetrapeptide-3, Beta-Sitosterol: the plant-based (not human-derived) biomimetic exosomes are an active that carries the other actives toward the follicle. Acetyl tetrapeptide-3 supports hair anchoring by supporting collagen III and laminin around the root; red clover, rich in biochanin A, conditions the scalp. Beta-sitosterol is a plant sterol that helps balance the scalp environment for stronger-looking, fuller-looking hair.
- Panthenol, Glycerin, Urea: Condition and moisturise hair and scalp.
- Hydrolyzed Soy Protein, wheat & soy germ extracts: Conditioning protein and botanicals that improve fibre feel and body.
- Niacinamide, Biotin, Pyridoxine HCl: B vitamins (B3, B7, B6) commonly used in hair care.
- Arginine, Ornithine, Citrulline, Glucosamine: Skin-conditioning amino acids and sugars.
- Ginseng, onion bulb, rosemary, Scutellaria extracts: Botanical scalp-conditioning extracts.
- Phytosphingosine, Phosphatidylcholine: Lipids that condition and support scalp comfort.
- Zinc PCA: Scalp conditioner commonly used for oily-prone scalps.
- Glycogen (marine glycogen): conditioning polysaccharide that adds moisture and helps keep the scalp in good condition.
- Helianthus Annuus Seed Oil (sunflower seed oil): nourishing plant oil that softens the hair fibre and adds scalp comfort.
- Ascorbic Acid (vitamin C): antioxidant that helps protect hair and scalp against oxidation.
- Coffea Arabica Fruit Extract (coffee fruit extract): antioxidant botanical extract that helps keep the scalp in good condition.
How to use
- Apply a small amount to wet hair, focusing on the scalp.
- Massage gently with your fingertips to lather.
- Leave on for 5 minutes before rinsing.
- Rinse thoroughly; repeat if needed.
- After washing, apply DNA Hairmax Pro Plus to the scalp (leave-in).
- Avoid contact with eyes; if it happens, rinse with water.
FAQ
Who is Hair Loss Prevention Shampoo Plus for?
For hair with early, seasonal or reactive thinning that looks finer or flatter. If shedding is sudden, heavy or patchy, see a dermatologist or trichologist.
What is the TFD System with biomimetic follicular-release exosomes?
It is the name used in SIMONE's hair fall range for its biomimetic follicular-release exosomes. Designed, plant-based vesicles (not human-derived) that mimic the structure of natural exosomes. In this shampoo they are an active ingredient that carries red clover extract, acetyl tetrapeptide-3 and beta-sitosterol toward the follicle.
How is it different from the other hair loss shampoos?
The Hair Fall & Strengthening category holds the full range. The TFD System with biomimetic follicular-release exosomes is in the shampoos and the mask; the leave-in lotions use their own actives. This is the shampoo for thinning hair; for colour-treated hair, choose Hair Loss & Colors Shampoo Plus.
What should I use with it?
DNA Hairmax Pro Plus, the leave-in step for the scalp after each wash. It is also part of the 3-step hair loss routine with mask and serum.
What sizes and prices are available?
250 ml (€22.32), 500 ml (€35.74) and 1000 ml (€64.33), VAT included, plus shipping.
Where is it made and what is in it?
It is formulated and made in our lab in Spain (Trichomedic Labs) under EU Regulation 1223/2009. The full INCI list is under Additional information and on the pack.
This product works best as part of a complete routine. See how to fit it into your step-by-step routine for hair fall and thinning hair.



























Reviews
There are no reviews yet.